Jan 22, 2020

Cancers evade immunotherapy by 'discarding the evidence' of tumor-specific mutations: Discovery could explain widespread acquired resistance among patients treated with immune checkpoint blockade drugs -- ScienceDaily

Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination of certain genetic mutations needed to enable the immune system to recognize and attack malignant cells.

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