Sep 16, 2021

Calcium channel blockers caught in the act at atomic level: Structural studies unlock basic mechanisms of common heart and blood pressure medications, and could lead to better drug design -- ScienceDaily

Atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects by acting at different sites on the calcium channel molecule. The study looked at the anti-arrhythmia drug verapamil, and the hypertension and angina drug amlodipine. The study was conducted on bacterial calcium channels, which respond...

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