Dec 17, 2019

The cost-effectiveness of returning incidental findings from next-generation genomic sequencing | Genetics in Medicine

The American College of Medical Genetics and Genomics (ACMG) recommended that clinical laboratories performing next-generation sequencing analyze and return pathogenic variants for 56 specific genes it considered medically actionable. Our objective was to evaluate the clinical and economic impact of returning these results. We developed a decision-analytic policy model to project the...

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