Oct 17, 2019

Identification of subepithelial mesenchymal cells that induce IgA and diversify gut microbiota | Nature Immunology

IgA is necessary for maintaining gut homeostasis, and its production depends on microbial sampling by the gut-associated lymphoid tissue (GALT). Takayanagi and colleagues identify a novel population of mesenchymal cells in the GALT that control M cell differentiation and function of gut epithelium.

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