Jan 20, 2020
Key clinical point: Substituting LCZ696 for enalapril in heart failure patients was linked with significant improvements in survival, heart failure hospitalization, and quality of life.Major finding: LCZ696 was associated with a 20% relative risk reduction in cardiovascular death and heart-failure hProceed to the page: http://linkis.com/Gona0
Novartis' new heart failure drug LCZ696 has caused a stir at the European Society of Cardiology meeting in Barcelona, with specialists lauding data showing its clear superiority over the ACE inhibitor enalapril. - News - PharmaTimes
Up to one-half of patients with heart failure (HF) have preserved ejection fraction (HFpEF). Although treatment of patients with HF and reduced ejection fraction (HFrEF) is well established and based on evidence from multiple randomized clinical trials, no evidence has been obtained to support any
An official journal of the European Society of Cardiology. Publishes high quality material, both clinical and scientific, on all aspects of Cardiovascular Medic
Background Troponins may be elevated in patients with pneumonia, but associations with myocardial infarction (MI) and with platelet activation are still undefined. Objectives The aim of this study was to investigate the relationship between troponin elevation and in vivo markers of platelet...
Background The prospective, randomized FREEDOM (Comparison of Two Treatments for Multivessel Coronary Artery Disease in Individuals With Diabetes) trial found coronary artery bypass graft surgery (CABG) was associated with better clinical outcomes than percutaneous coronary intervention (PCI) in...
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SILVER SPRING, MD. – A Food and Drug Administration advisory panel unanimously voted in favor of accelerated approval for a novel drug to treat primary biliary
In the 3 years following bariatric surgery, 50%-70% of adults will experience clinically meaningful easing of bodily pain and improved physical function, a collaborative study shows.
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