Jun 16, 2016

Disruption of the sugar sensing receptor T1R2 attenuates metabolic derangements associated with diet-induced obesity | Endocrinology and Metabolism

Sweet taste receptors (STRs) on the tongue mediate gustatory sweet sensing, but their expression in the gut, pancreas and adipose tissue suggests a physiological contribution to whole-body nutrient sensing and metabolism. However, little is known about the function and contribution of these sugar sensors during metabolic stress induced by over-nutrition and subsequent obesity. Here we investigate...

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